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Pasireotide ditrifluoroacetate
CAS No. ——
Pasireotide ditrifluoroacetate( SOM230 ditrifluoroacetate )
Catalog No. M16968 CAS No. ——
A potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePasireotide ditrifluoroacetate
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors.
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DescriptionA potent, stable cyclohexapeptide somatostatin mimic that exhibits unique high-affinity binding to human somatostatin receptors (pKi=8.2/9.0/9.1/<7.0/9.9 for sst1/2/3/4/5, respectively); effectively inhibits GHRH-induced growth hormone release in primary cultures of rat pituitary cells with IC50 of 0.4 nM, also potently suppresses GH secretion in rats.Cushing's Disease Approved.
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In Vitro——
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In Vivo——
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SynonymsSOM230 ditrifluoroacetate
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PathwayGPCR/G Protein
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TargetSomatostatin Receptor
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RecptorSomatostatin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight1275.253
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Molecular FormulaC62H68F6N10O13
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILES——
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Chemical NameCyclo[(2S)-2-phenylglycyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-L-tyrosyl-L-phenylalanyl-(4R)-4-[[[(2-aminoethyl)amino]carbonyl]oxy]-L-prolyl], di(trifluoroacetate) (9CI)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Cortistatin-14
Cortistatin 14 is a neuropeptide expressed in inhibitory neurons of the cerebral cortex. Depresses neuronal activity, and induces slow-wave sleep, likely through antagonism of acetylcholine. It is structurally and functionally similar to somatostatin 14. Competes with somatostatin 14 for binding of somatostatin receptors (IC50s=5, 0.09, 0.3, 0.2, and 0.3nM for receptors sst1-5, respectively).
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CYN 154806
CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist, The pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
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Octreotide acetate
An octapeptide that mimics natural somatostatin pharmacologically, that is 200 times more potent than somatostatin.
